Hyalmass Aqua-Exosome is Maypharm’s hybrid hydration booster combining high-molecular-weight hyaluronic acid, exosomes and PDRN in 2.5 mL prefilled syringes, ten per box. Launched in late 2024, it is positioned for skin hydration, elasticity and regeneration, with the brand owner describing both mesotherapy use and derma-roller-assisted topical application in three sessions at three-to-five-week intervals. Professional use only.
What is Hyalmass Aqua-Exosome?
Hyalmass Aqua-Exosome is Maypharm’s hybrid hydration booster launched at the end of 2024, combining high-molecular-weight hyaluronic acid, exosomes and PDRN in 2.5 mL prefilled syringes, ten to a box. Maypharm describes the three components as working together — HA for immediate hydration, exosomes for cellular signalling and regeneration, PDRN for tissue repair and elasticity — and positions the product for skin hydration, elasticity and regeneration.
How does it compare with other exosome products?
Most exosome products Lyderma stocks are lyophilised two-vial kits for topical post-procedure use, such as Exo’One and ASCE+ SRLV. Hyalmass Aqua-Exosome is instead a ready-to-use HA gel with exosomes and PDRN already combined, in ten prefilled syringes. Maypharm’s own materials describe both mesotherapy use and derma-roller-assisted topical application, so the delivery route is the practitioner’s call.
| Hyalmass Aqua-Exosome | HA + exosomes + PDRN ready-to-use · 10 × 2.5 mL syringes |
|---|---|
| Exo’One | Lyophilised exosome 50 mg + HA 5 mL · two-vial topical kit |
| ASCE+ SRLV | Lyophilised plant-exosome 20 mg + diluent · topical kit |
| AMI Tone Up | PN + vegan exosome + glutathione · 6 × 5 mL |
What do clinics use Hyalmass Aqua-Exosome for?
It is commonly selected for hydration-led rejuvenation with an exosome and PDRN component, and as a post-microneedling booster. Maypharm’s listed guidance is application to the facial areas (avoiding the eye area) with derma-roller or pen to enhance absorption, in three applications at three-to-five-week intervals; its launch materials also describe mesotherapy use. Technique and suitability are decided by the treating clinician.
Commonly selected for
- Hydration programmes with an exosome element
- Post-microneedling booster courses
- Dull, dehydrated or tired skin
- Ten-syringe packs for multi-patient clinic use
How is it supplied?
Ten 2.5 mL prefilled syringes per box. Store and handle per the manufacturer’s instructions for use.
Reviewed against publicly available manufacturer information. Indications, dosing and technique are product-specific per the manufacturer’s labeling and are decided by the treating clinician.
Specifications
| Brand | Hyalmass (Maypharm) |
|---|---|
| Brand owner | Maypharm Co., Ltd. (Seoul, South Korea) |
| Origin | South Korea |
| Active | HA · exosomes · PDRN |
| Composition | High-molecular-weight hyaluronic acid, exosomes (stem-cell-derived and plant-derived per brand owner) and PDRN — amounts not published |
| Format | 2.5 mL prefilled syringe |
| Presentation | 10 prefilled syringes per box |
| Areas | Face — hydration · regeneration |
| Delivery | Brand owner describes both mesotherapy use and topical application with derma-roller/pen; 3 applications at 3–5-week intervals |
| Administration | Professional use only |
| Storage & handling | Store and handle per the manufacturer’s instructions for use |
Frequently asked questions
What is Hyalmass Aqua-Exosome used for?
For skin hydration, elasticity and regeneration — a hybrid booster of hyaluronic acid, exosomes and PDRN, often used as a post-microneedling course.
Is it injected or applied topically?
Maypharm’s materials describe both: mesotherapy use in its launch release, and topical application with a derma-roller or pen in its product listing. The treating clinician decides the route.
What is the exosome source?
Maypharm describes the exosomes as derived from stem-cell conditioned media and plant sources. Amounts are not published.
How does it differ from a two-vial exosome kit?
Two-vial kits such as Exo’One are lyophilised powders reconstituted before use; Hyalmass Aqua-Exosome is a ready-to-use HA gel with exosomes and PDRN already combined in prefilled syringes.
How is it supplied?
Ten 2.5 mL prefilled syringes per box. Store per the manufacturer’s instructions.