Rejuran Healer Black is a polynucleotide (PN) skin booster from PharmaResearch (South Korea). Each box holds two 2 mL prefilled syringes of purified salmon-DNA polynucleotide, injected intradermally to support skin regeneration, elasticity and texture across the face, neck and décolleté. It is intended for administration by qualified medical professionals.
What is Rejuran Healer Black?
Rejuran Healer Black is part of PharmaResearch’s Rejuran range of injectable polynucleotide (PN) skin boosters. Unlike a dermal filler, it is not designed to add volume — it is a skin-quality product positioned to support the skin’s own regeneration and resilience. The active PN is derived from the DNA of Korean chum salmon (Oncorhynchus keta) and purified with the company’s proprietary DOT™ technology.
The “Black” edition is supplied as two ready-to-use 2 mL prefilled syringes per box, commonly selected by clinics for full-face skin-quality protocols.
How does polynucleotide (PN) work in the skin?
Polynucleotides are long chains of nucleotides — the building blocks of DNA. Placed in the dermis, they are designed to act as a scaffold and signalling material that supports fibroblast activity and the skin’s natural repair processes, which practitioners associate with improved hydration, firmness and texture over a course of sessions.
Intradermal delivery
PN is injected into the dermis in fine deposits across the treatment area.
Support & scaffold
The polynucleotide chain is designed to support the local repair environment and fibroblast activity.
Skin-quality change
Practitioners commonly report gradual gains in elasticity, hydration and texture across sessions.
Maintenance
A short course is typically followed by periodic maintenance, per the practitioner’s protocol.
What is Rejuran Healer Black used for?
It is commonly selected for overall skin-quality improvement — supporting elasticity, hydration and fine-texture refinement on the face, neck and décolleté. Because it targets skin quality rather than volume, clinics often position it alongside, not instead of, HA fillers and toxins within a treatment plan.
Where is it used, and who is it for?
Because Rejuran Healer Black targets skin quality rather than volume, clinics select it for patients who want smoother, firmer, better-hydrated skin rather than added contour. It is commonly applied across three areas:
Face
Overall texture, fine-line softening, elasticity and a fresher, more even glow.
Neck
Crepey, thin skin where firmness and hydration tend to fade first.
Décolleté
Sun-exposed chest skin prone to dryness, fine lines and loss of tone.
Commonly selected for
- Dull, tired or dehydrated-looking skin that needs a quality reset
- Early loss of elasticity and fine textural lines
- Patients seeking skin-quality results without added volume
- Pre-event skin preparation and ongoing maintenance
- Combination plans alongside HA fillers or toxins
Suitability, areas and technique are always assessed by the treating clinician for each individual.
Specifications
| Brand | REJURAN® (PharmaResearch) |
|---|---|
| Manufacturer | PharmaResearch Co., Ltd. (South Korea) |
| Origin | South Korea |
| Active | Polynucleotide (PN) |
| Purification | Proprietary DOT™ technology |
| Presentation | 2 prefilled syringes, ready to use |
| Format | 2 × 2 mL prefilled |
| Volume | 2 × 2 mL |
| Areas | Face · Neck · Décolleté |
| Administration | Intradermal — by a qualified medical professional only |
| Storage & handling | Store and handle per the manufacturer’s instructions for use |
Frequently asked questions
What is Rejuran Healer Black used for?
It is a polynucleotide skin booster used to support overall skin quality — elasticity, hydration and texture — on the face, neck and décolleté. It targets skin quality rather than adding volume.
Is Rejuran the same as a dermal filler?
No. A hyaluronic-acid dermal filler is designed to add volume or contour. Rejuran Healer Black is a skin booster designed to support the skin’s own regeneration and resilience.
How many sessions are usually needed?
Skin boosters are typically given as a short course of sessions a few weeks apart, then maintained periodically. The exact number is decided by the treating clinician; follow the manufacturer’s instructions for use.
What is the difference between PN and PDRN?
Both are salmon-DNA-derived. Polynucleotide (PN) refers to longer nucleotide chains, while PDRN refers to shorter fragments. Rejuran is positioned as a polynucleotide (PN) product.
How should Rejuran Healer Black be stored and handled?
Store and handle strictly according to PharmaResearch’s instructions for use, and administer only within its intended professional setting.