HP Vitaran® PN Skinbooster — Polynucleotide 20 mg/mL Intradermal Gel (2 × 1 mL)

What is HP Vitaran PN?

HP Vitaran PN is BR Pharm’s polynucleotide intradermal gel — one of the few Korean PN boosters supplied with a Korean MFDS Class IV medical-device approval and a CE mark. Each 1 mL prefilled syringe contains 20 mg of polynucleotide sodium (2%) derived from salmon trout, with no lidocaine; a box holds two syringes, each with a 33G/4 mm needle. The MFDS-labelled indication is the temporary improvement of crow’s-feet fine wrinkles in adults.

Vitaran PN, Vitaran i or Rejuran — how do they differ?

All three Vitaran SKUs share the same 20 mg/mL polynucleotide and the same MFDS approval; BR Pharm differentiates them by viscosity and needle. Vitaran PN is the mid-viscosity, all-purpose formula (33G). Vitaran i is the lowest-viscosity version with a 34G needle for thin, eye-area skin. Against Rejuran Healer, Vitaran PN offers a comparable 2% PN concentration in a 1 mL format with device-level approval at a lower entry price.

HP Vitaran PN	PN 20 mg/mL · 2 × 1 mL · mid viscosity · 33G · MFDS Class IV
HP Vitaran i	PN 20 mg/mL · 2 × 1 mL · low viscosity · 34G · eye area
Rejuran Healer	Polynucleotide · 2 × 2 mL · dermal repair
AMI Plus X	PN 2% (40 mg / 2 mL) · 1 syringe

What do clinics use Vitaran PN for?

Its labelled indication is crow’s-feet fine wrinkles; in practice clinics select it for polynucleotide skin-quality work across the face — fine lines, texture and regeneration — where an approved device-class PN with a fine 33G needle is wanted. BR Pharm does not publish a session protocol; number and spacing of sessions follow the practitioner’s judgement. Suitability is assessed by the treating clinician.

Commonly selected for

• Crow’s feet and periorbital fine lines
• Full-face PN regeneration courses
• Clinics that require MFDS device approval and CE marking
• Value alternative to premium PN brands

How is Vitaran PN supplied and stored?

Two 1 mL prefilled syringes per box with 33G/4 mm needles. Store at 1–30 °C protected from light; shelf life three years from manufacture. BR Pharm’s U.S. MoCRA registration relates to its cosmetic lines and is not an FDA approval of this device.

Reviewed against publicly available manufacturer information. Indications, dosing and technique are product-specific per the manufacturer’s labeling and are decided by the treating clinician.

Specifications

Brand	HP Vitaran® (BR Pharm)
Manufacturer	BR PHARM Co., Ltd. (Wonju, South Korea)
Origin	South Korea
Active	Polynucleotide sodium 20 mg/mL (2%)
Composition	Polynucleotide sodium 20 mg per 1 mL prefilled syringe, salmon-trout-derived; no lidocaine
Format	1 mL prefilled syringe
Presentation	2 prefilled syringes per box; 33G / 4 mm needle
Areas	Crow’s feet · face fine lines
Viscosity	Mid (●●) — between Vitaran i (●) and Vitaran S (●●●)
Regulatory	Korea MFDS-approved Class IV medical device (tissue-repair biomaterial, approval 제허 23-784호) · CE-marked (EU MDR certification announced by BR Pharm, 2026)
Administration	Intradermal injection — by a qualified medical professional only
Storage & handling	1–30 °C, protected from light; shelf life 3 years (manufacturer)

Frequently asked questions