SKINVIVE by JUVÉDERM is Allergan Aesthetics’ hyaluronic acid microdroplet injectable: 12 mg/mL cross-linked HA with 0.3% lidocaine in two 1 mL prefilled syringes, each with two 32G needles. It is injected intradermally across the cheeks to improve skin smoothness and hydration, with results the manufacturer cites as lasting up to six months. FDA-approved in the U.S. in May 2023 and marketed elsewhere as JUVÉDERM VOLITE (CE Class III). Store at room temperature; professional use only.
What is SKINVIVE by JUVÉDERM?
SKINVIVE is Allergan Aesthetics’ hyaluronic acid microdroplet injectable — a skin-quality product rather than a volumising filler. Each 1.0 mL prefilled syringe contains 12 mg/mL of cross-linked HA with 0.3% lidocaine, and the box holds two syringes, each with two 32G needles. It is injected intradermally as a grid of tiny microdroplets across the cheeks to improve skin smoothness and hydration, with the manufacturer citing results lasting up to six months with optimal treatment.
In the United States it is the first and only FDA-approved HA microdroplet injectable for improving cheek skin smoothness (PMA P110033/S059, approved May 2023). Outside the U.S. the same product has been marketed since 2016 as JUVÉDERM® VOLITE, a CE-marked Class III device, with the SKINVIVE name rolled out to 35 further markets in 2025.
How is SKINVIVE different from a Juvéderm filler or a Korean skin booster?
Fillers such as Juvéderm Ultra 3 are placed deeper to lift and shape. SKINVIVE uses a low HA concentration in a soft gel placed intradermally in microdroplets, so it hydrates and smooths without adding contour. Against non-cross-linked boosters such as Hyaron, its light cross-linking is what gives the longer duration.
| SKINVIVE | Cross-linked HA 12 mg/mL + 0.3% lidocaine · 2 × 1 mL · cheek smoothness, up to 6 months |
|---|---|
| Restylane Skinboosters Vital | Stabilised HA 20 mg/mL + 0.3% lidocaine · 1 × 1 mL · skin hydration and elasticity |
| Profhilo | Hybrid HA 64 mg per 2 mL, no cross-linker · bio-remodelling of laxity |
| Hyaron | Non-cross-linked HA 10 mg/mL · 10 × 2.5 mL · hydration mesotherapy |
What is SKINVIVE used for?
Its U.S. indication is intradermal injection to improve skin smoothness of the cheeks in adults over 21. The EU indication for VOLITE covers superficial cutaneous depressions such as fine lines and improvement of skin-quality attributes including hydration and elasticity. Injection pattern, volume per point and retreatment are decided by the treating clinician in line with the manufacturer’s directions for use.
Commonly selected for
- Cheek skin smoothness and “glow” without volume
- Fine lines and dehydrated, rough-textured skin
- Patients asking for an FDA-approved skin booster by name
- Practices already using the Juvéderm portfolio
How is SKINVIVE supplied and stored?
Two 1.0 mL prefilled luer-lock syringes per box, each sealed in a tray with two sterile 32G ½″ needles. Store at room temperature up to 25 °C and do not freeze. The pack supplied by Lyderma is the international presentation; regulatory status and labelling follow the market of supply.
Reviewed against publicly available manufacturer information. Indications, dosing and technique are product-specific per the manufacturer’s labeling and are decided by the treating clinician.
Specifications
| Brand | SKINVIVE™ by JUVÉDERM® (Allergan Aesthetics, an AbbVie company) |
|---|---|
| Manufacturer | Allergan — made in France |
| Origin | France |
| Active | HA 12 mg/mL + lidocaine 0.3% |
| Format | 1.0 mL prefilled syringe |
| Presentation | 2 syringes per box, each with 2 × 32G ½″ needles |
| Areas | Cheeks (intradermal) |
| Regulatory | FDA-approved in the United States (PMA P110033/S059, May 2023); marketed outside the U.S. as JUVÉDERM® VOLITE, CE-marked Class III |
| Administration | Injectable — by a qualified medical professional only |
| Storage & handling | Room temperature up to 25 °C; do not freeze (manufacturer) |
| Composition | Hyaluronic acid 12 mg/mL (Streptococcus-derived, BDDE cross-linked) + lidocaine 0.3% w/w |
Frequently asked questions
What does SKINVIVE do?
It is injected as tiny microdroplets into the skin of the cheeks to improve smoothness and hydration — a skin-quality treatment, not a volumising filler. The manufacturer cites results lasting up to six months with optimal treatment.
Is SKINVIVE FDA-approved?
Yes. SKINVIVE by JUVÉDERM was FDA-approved in May 2023 (PMA P110033/S059) for intradermal injection to improve cheek skin smoothness in adults over 21. Outside the U.S. the product is marketed as JUVÉDERM VOLITE with CE marking.
Does it contain lidocaine?
Yes — 0.3% lidocaine is built into the gel for comfort during injection.
What is in the box?
Two 1.0 mL prefilled luer-lock syringes, each packed with two sterile 32G ½″ needles.
How should SKINVIVE be stored?
At room temperature up to 25 °C, protected from freezing, per Allergan’s directions for use.