Juvéderm Ultra Smile is the lip-dedicated member of the Juvéderm Ultra range from Allergan Aesthetics (AbbVie), supplied as two 0.55 mL prefilled syringes at 24 mg/mL cross-linked hyaluronic acid with 0.3% lidocaine. It is selected for lip volume, lip shape and border definition, and the vertical lines around the mouth. Injection depth and technique are product-specific per the manufacturer’s labeling, and it is intended for administration by qualified medical professionals.
What is Juvéderm Ultra Smile?
Juvéderm Ultra Smile is the lip-dedicated member of the Juvéderm Ultra range from Allergan Aesthetics, an AbbVie company. It is a cross-linked hyaluronic acid gel at 24 mg/mL with 0.3% lidocaine, supplied as two 0.55 mL prefilled syringes — the smaller syringe size that suits lip work, where product is placed in small, controlled amounts.
The rest of the Ultra range is numbered by how the gel behaves across the face. Ultra Smile is named rather than numbered because it is positioned for one region: the lips and the area immediately around the mouth.
How does Juvéderm Ultra Smile compare with the numbered Ultra range?
All four share the same 24 mg/mL hyaluronic acid concentration and 0.3% lidocaine. What changes is the gel’s firmness, the plane it is placed in and the syringe size. Ultra Smile shares the smaller 0.55 mL syringe with Ultra 2, but it is positioned for lip volume and shape rather than fine surface lines.
| Juvéderm Ultra Smile | 24 mg/mL HA · 0.3% lidocaine · 2 × 0.55 mL · lips and perioral · lip volume, shape, vertical lip lines |
|---|---|
| Juvéderm Ultra 2 | 24 mg/mL HA · 0.3% lidocaine · 2 × 0.55 mL · superficial-to-mid dermis · fine lines, lip contour |
| Juvéderm Ultra 3 | 24 mg/mL HA · 0.3% lidocaine · 2 × 1 mL · mid-to-deep dermis · folds, lips, contour |
| Juvéderm Ultra 4 | 24 mg/mL HA · 0.3% lidocaine · 2 × 1 mL · deep dermis and deeper · volume, projection, deep folds |
What is Juvéderm Ultra Smile used for?
It is commonly selected for lip enhancement — adding volume to the lip body, redefining lip shape and the vermilion border, and softening the vertical lines around the mouth. The premixed lidocaine matters here in particular, because the lips are among the most sensitive areas treated. Injection depth, volume and technique are product-specific per the manufacturer’s labeling and are decided by the treating clinician.
Commonly selected for
- Lip volume and fullness
- Lip shape and vermilion border definition
- Vertical lip lines and the perioral area
- Treatments where a small, precisely placed volume is preferred
Hyaluronic acid fillers work by binding water in the tissue, so results are visible immediately and soften gradually as the gel is metabolised. Duration varies with the product, the area treated, the volume placed and the individual patient — lips are a mobile area and are commonly reviewed sooner than static areas of the face.
Specifications
| Brand | Juvéderm® (Allergan Aesthetics) |
|---|---|
| Manufacturer | Allergan — an AbbVie company |
| Range | Juvéderm Ultra |
| Active | Cross-linked hyaluronic acid, 24 mg/mL |
| Anaesthetic | Lidocaine hydrochloride, 0.3% (3 mg/mL) |
| Format | 2 × 0.55 mL prefilled syringes |
| Indication | Lip enhancement and the perioral area (product-specific) |
| Areas | Lip body · Lip border · Vertical lip lines (product-specific) |
| Regulatory | CE-marked; several Juvéderm products are FDA-approved in the U.S. (product-specific by market) |
| Administration | Injectable — by a qualified medical professional only |
| Storage & handling | Store and handle per the manufacturer’s instructions for use |
Frequently asked questions
What is Juvéderm Ultra Smile used for?
It is commonly selected for lip enhancement — adding volume to the lip body, redefining lip shape and the vermilion border, and softening vertical lines around the mouth. Indications and technique are product-specific per the manufacturer’s labeling.
What is the difference between Juvéderm Ultra Smile and Ultra 2?
Both are 24 mg/mL cross-linked hyaluronic acid with 0.3% lidocaine in two 0.55 mL syringes. Ultra 2 is positioned for fine superficial lines and lip contour; Ultra Smile is positioned for the lips themselves — volume, shape and the perioral area.
Does Juvéderm Ultra Smile contain lidocaine?
Yes — it contains 0.3% lidocaine hydrochloride (3 mg/mL), premixed. That matters in lip treatment in particular, as the lips are among the most sensitive areas treated.
How is Juvéderm Ultra Smile supplied?
As two 0.55 mL prefilled syringes per box, ready to use.
How should Juvéderm Ultra Smile be stored and handled?
Store and handle strictly according to the manufacturer’s instructions for use, and administer only within its intended professional setting.