Rejuran HB (Hydro Booster) is a polynucleotide product from PharmaResearch that combines PN, purified with DOT™ technology from salmon DNA, with non-crosslinked hyaluronic acid and 0.3% lidocaine in a single 1 mL prefilled syringe. The PN supports the skin’s own regeneration over a course of sessions while the hyaluronic acid delivers immediate hydration. It is a skin-quality product rather than a volumising filler, and is intended for administration by qualified medical professionals.
What is Rejuran HB?
Rejuran HB — the “Hydro Booster” of PharmaResearch’s Rejuran range — combines polynucleotide (PN), purified with the company’s DOT™ technology from salmon DNA, with non-crosslinked hyaluronic acid in a single ready-to-use 1 mL prefilled syringe. It also contains 0.3% lidocaine for comfort during treatment.
The combination is the point: the polynucleotide supports the skin’s own regeneration over a course of sessions, while the hyaluronic acid brings immediate hydration on placement.
How is Rejuran HB different from Rejuran Healer and Rejuran S?
All three are polynucleotide products from the same manufacturer, built for different jobs. HB is the one that adds hyaluronic acid, so it pairs regeneration with instant hydration and is supplied with lidocaine premixed.
| Rejuran Healer | PN only · 2 × 2 mL · broad skin-quality treatment |
|---|---|
| Rejuran S | Long-chain, high-viscosity PN · 1 × 1 mL · localised scars and texture |
| Rejuran HB | PN + non-crosslinked HA, with lidocaine · 1 × 1 mL · regeneration plus immediate hydration |
| Rejuran I | Low-viscosity PN · 1 × 1 mL · the delicate eye area |
What is Rejuran HB used for?
It is commonly selected for combined skin regeneration and hydration — skin that has lost both elasticity and moisture, and full-face biorevitalisation where a single-syringe treatment is convenient. Because the hyaluronic acid is non-crosslinked, it is positioned as a skin-quality product rather than a volumising filler. Indications, depth and technique are product-specific per the manufacturer’s labeling and are decided by the treating clinician.
Commonly selected for
- Skin showing both dehydration and early loss of elasticity
- Patients who want hydration they can see immediately, plus gradual skin-quality change
- Full-face treatment where one prefilled syringe is practical
- Treatment plans where injection comfort matters
Treatment is typically delivered as a short course of sessions spaced a few weeks apart, per the practitioner’s protocol. Suitability is always assessed by the treating clinician.
Specifications
| Brand | REJURAN® (PharmaResearch) |
|---|---|
| Manufacturer | PharmaResearch (South Korea) |
| Origin | South Korea |
| Active | Polynucleotide (PN, DOT™ purified) + non-crosslinked hyaluronic acid |
| Anaesthetic | Lidocaine 0.3% |
| Format | 1 × 1 mL prefilled syringe |
| Presentation | 1 prefilled syringe, ready to use |
| Areas | Face · Neck — skin quality and hydration (product-specific) |
| Administration | Injectable — by a qualified medical professional only |
| Storage & handling | Store and handle per the manufacturer’s instructions for use |
Frequently asked questions
What is Rejuran HB used for?
It is commonly selected for combined skin regeneration and hydration — skin that has lost both moisture and elasticity — and for full-face biorevitalisation using a single prefilled syringe. Indications are product-specific per the manufacturer’s labeling.
What is the difference between Rejuran HB and Rejuran Healer?
Healer contains polynucleotide only and comes as two 2 mL syringes. HB adds non-crosslinked hyaluronic acid and lidocaine in a single 1 mL syringe, so it pairs regeneration with immediate hydration and a more comfortable injection.
Does Rejuran HB contain lidocaine?
Yes — it contains 0.3% lidocaine, premixed, to improve comfort during treatment.
Is Rejuran HB a dermal filler?
No. Its hyaluronic acid is non-crosslinked, so it is positioned as a skin-quality and hydration product rather than a filler designed to add volume or contour.
How should Rejuran HB be stored and handled?
Store and handle strictly according to the manufacturer’s instructions for use, and administer only within its intended professional setting.